Necrose du segment anterieur sur keratomycose a Fusarium polyresistant. A propos d'un cas. [Anterior segment necrosis in multidrug-resistant Fusarium keratomycosis: a case study]

Details

Serval ID
serval:BIB_3322031439F8
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Necrose du segment anterieur sur keratomycose a Fusarium polyresistant. A propos d'un cas. [Anterior segment necrosis in multidrug-resistant Fusarium keratomycosis: a case study]
Journal
Journal Français d'Ophtalmologie
Author(s)
Gianoli  F., Guex-Crosier  Y., Marchetti  O., Wolfensberger  T. J., Spahn  B.
ISSN
0181-5512 (Print)
Publication state
Published
Issued date
05/2005
Volume
28
Number
5
Pages
498-501
Notes
Case Reports
English Abstract
Journal Article --- Old month value: May
Abstract
Keratomycosis is a rare sight-threatening infection of the cornea, with greater morbidity than bacterial keratitis. Predisposing factors in its pathogenesis are corneal trauma, mostly of plant origin, and overuse of topical corticosteroids, associated or not with antibiotics. We report a case of a 71-year-old man who developed Fusarium (lichenicola or solani) keratitis, 15 days after beginning topical therapy with a corticosteroid and antibiotic. Despite aggressive antifungal therapy with fluconazole, he required a penetrating keratoplasty for impending corneal perforation, and finally, even after systemic use of itraconazole and topical use of amphotericin B, the infection progressed and an evisceration was required. In the evisceration material, a multidrug-resistant Fusarium lichenicola or solani, was found, partially sensitive to voriconazole only.
Keywords
Aged Antifungal Agents/therapeutic use Corneal Diseases/*diagnosis/*surgery Drug Resistance, Multiple *Eye Enucleation *Fusarium Humans Male Mycoses/*diagnosis
Pubmed
Web of science
Create date
28/01/2008 13:05
Last modification date
20/08/2019 13:18
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