Associations between Red Blood Cell and Platelet Transfusions and Retinopathy of Prematurity.
Details
Serval ID
serval:BIB_32986BFFA07E
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Associations between Red Blood Cell and Platelet Transfusions and Retinopathy of Prematurity.
Journal
Neonatology
Working group(s)
Swiss Neonatal Network
ISSN
1661-7819 (Electronic)
ISSN-L
1661-7800
Publication state
Published
Issued date
08/12/2020
Peer-reviewed
Oui
Volume
117
Number
5
Pages
1-7
Language
english
Notes
Publication types: Journal Article
Publication Status: aheadofprint
Publication Status: aheadofprint
Abstract
The aim of this study is to examine possible associations between the transfusion of RBC or platelets (PLTs) and the development of retinopathy of prematurity (ROP) in infants.
This retrospective, national, case-control study included all live births in Switzerland between 2013 and 2018. We investigated preterm infants at a gestational age of <28 weeks, who developed higher stage ROP (≥stage 2, n = 178). Each case infant was matched to another of the same sex who did not develop ROP (n = 178, control group).
When compared with the control group, we observed higher numbers of RBC transfusions per infant and higher percentages of infants receiving PLT transfusions in the case group. An adjusted logistic regression analysis revealed that both RBC (odds ratio [OR] 1.081, 95% confidence interval [CI] 1.020-1.146) and PLT transfusions (OR = 2.502, 95% CI 1.566-3.998) numbers were associated with ROP development.
Multiple RBC and PLT transfusions are associated with higher stage ROP development. Prospective studies are required to determine their potential as risk factors.
This retrospective, national, case-control study included all live births in Switzerland between 2013 and 2018. We investigated preterm infants at a gestational age of <28 weeks, who developed higher stage ROP (≥stage 2, n = 178). Each case infant was matched to another of the same sex who did not develop ROP (n = 178, control group).
When compared with the control group, we observed higher numbers of RBC transfusions per infant and higher percentages of infants receiving PLT transfusions in the case group. An adjusted logistic regression analysis revealed that both RBC (odds ratio [OR] 1.081, 95% confidence interval [CI] 1.020-1.146) and PLT transfusions (OR = 2.502, 95% CI 1.566-3.998) numbers were associated with ROP development.
Multiple RBC and PLT transfusions are associated with higher stage ROP development. Prospective studies are required to determine their potential as risk factors.
Keywords
Platelet transfusion, Red blood cell transfusion, Retinopathy of prematurity
Pubmed
Web of science
Open Access
Yes
Create date
14/12/2020 11:50
Last modification date
16/04/2024 7:11
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