Membrane fluidization triggers membrane remodeling which affects the thermotolerance in Escherichia coli.

Détails

ID Serval
serval:BIB_31EEB8836942
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Membrane fluidization triggers membrane remodeling which affects the thermotolerance in Escherichia coli.
Périodique
Biochemical and Biophysical Research Communications
Auteur(s)
Shigapova N., Török Z., Balogh G., Goloubinoff P., Vígh L., Horváth I.
ISSN
0006-291X (Print)
ISSN-L
0006-291X
Statut éditorial
Publié
Date de publication
2005
Volume
328
Numéro
4
Pages
1216-1223
Langue
anglais
Résumé
Treatment of Escherichia coli with non-lethal doses of heat or benzyl alcohol (BA) causes transient membrane fluidization and permeabilization, and induces the rapid transcription of heat-shock genes in a sigma32-dependent manner. This early response is followed by a rapid adaptation (priming) of the cells to otherwise lethal elevated temperature, in strong correlation with an observed remodeling of the composition and alkyl chain unsaturation of membrane lipids. The acquisition of cellular thermotolerance in BA-primed cells is unrelated to protein denaturation and is not accompanied by the formation of major heat-shock proteins, such as GroEL and DnaK. This suggests that the rapid remodeling of membrane composition is sufficient for the short-term bacterial thermotolerance.
Mots-clé
Adaptation, Physiological/drug effects, Adaptation, Physiological/physiology, Benzyl Alcohol/pharmacology, Cell Membrane Permeability/drug effects, Cell Membrane Permeability/physiology, Dose-Response Relationship, Drug, Dose-Response Relationship, Radiation, Escherichia coli/drug effects, Escherichia coli/physiology, Heat-Shock Response/drug effects, Heat-Shock Response/physiology, Hot Temperature, Membrane Fluidity/drug effects, Membrane Fluidity/physiology
Pubmed
Web of science
Création de la notice
24/01/2008 21:02
Dernière modification de la notice
20/08/2019 14:17
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