Does differential visual exploration contribute to visual memory impairments in 22q11.2 microdeletion syndrome?

Details

Serval ID
serval:BIB_31B9B0144B20
Type
Article: article from journal or magazin.
Collection
Publications
Title
Does differential visual exploration contribute to visual memory impairments in 22q11.2 microdeletion syndrome?
Journal
Journal of intellectual disability research
Author(s)
Bostelmann M., Glaser B., Zaharia A., Eliez S., Schneider M.
ISSN
1365-2788 (Electronic)
ISSN-L
0964-2633
Publication state
Published
Issued date
12/2017
Peer-reviewed
Oui
Volume
61
Number
12
Pages
1174-1184
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
Chromosome 22q11.2 microdeletion syndrome (22q11.2DS) is a genetic syndrome characterised by a unique cognitive profile. Individuals with the syndrome present several non-verbal deficits, including visual memory impairments and atypical exploration of visual information. In this study, we seek to understand how visual attention may contribute to memory difficulties in 22q11.2DS by tracking eye movements during the encoding phase of a visual short-term memory task.
Eye movements were recorded during a computerised version of the multiple-choice Benton Visual Retention Test, which consisted of exploring and then recognising complex visual stimuli. Seventy-four participants affected by 22q11.2DS were compared with 70 typically developing participants.
Participants with 22q11.2DS performed less well than healthy controls on the task and spent more time and fixations on the principal (larger central) figures and less time and fixations on the smaller peripheral figures within the stimuli.
This study is the first to investigate visual attention in 22q11.2DS during a memory task. The results delineate impaired processes during encoding that affect visual memory performance. The findings may be especially useful for informing interventions intended to boost visual learning in patients with 22q11.2DS.
Keywords
Adolescent, Adult, Attention/physiology, Child, DiGeorge Syndrome/complications, DiGeorge Syndrome/physiopathology, Female, Humans, Male, Memory Disorders/etiology, Memory Disorders/physiopathology, Memory, Short-Term/physiology, Pattern Recognition, Visual/physiology, Young Adult, 22q11.2 microdeletion syndrome, encoding, eye movements, visual attention, visual short-term memory
Pubmed
Web of science
Create date
22/11/2017 9:42
Last modification date
20/08/2019 13:17
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