Characterisation of the prodrome to a first episode of psychotic mania: results of a retrospective study.

Détails

ID Serval
serval:BIB_319756AE954E
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Characterisation of the prodrome to a first episode of psychotic mania: results of a retrospective study.
Périodique
Journal of Affective Disorders
Auteur(s)
Conus P., Ward J., Lucas N., Cotton S., Yung A.R., Berk M., McGorry P.D.
ISSN
1573-2517[electronic], 0165-0327[linking]
Statut éditorial
Publié
Date de publication
2010
Peer-reviewed
Oui
Volume
124
Numéro
3
Pages
341-345
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Résumé
BACKGROUND: Little is known about the early phases of bipolar disorders (BPAD) and most of current knowledge derives from putative "high-risk" studies conducted in populations of bipolar off-spring; such information may therefore be relevant only to a sub-group of at-risk subjects. METHODS: Retrospective assessment of the phase preceding the emergence of mania and of premorbid characteristics of patients treated for a first episode of psychotic mania. The collected data was used mainly to generate hypotheses. RESULTS: Before onset of a first episode of psychotic mania, patients go through a phase of change from previous mental state where they present mood symptoms, sleep disruption and general functional decline. These clinical manifestations are however likely to have low specificity. However, their occurrence in patients presenting certain risk factors or markers of vulnerability that were identified at a relatively high prevalence in our sample, may be an indicator of impending first episode mania. LIMITATIONS: This is a retrospective study, in a small sample of patients presenting with psychotic mania. Criteria identified need therefore to be validated in larger prospective studies. CONCLUSIONS: Early identification of patients at risk to develop a first episode of psychotic mania is unlikely to be possible on the basis of symptoms alone. However, the occurrence of certain clinical characteristics in patients who have risk factors or markers of vulnerability to BPAD could be a sign of impending first episode mania.
Pubmed
Web of science
Création de la notice
23/08/2010 14:49
Dernière modification de la notice
20/08/2019 14:16
Données d'usage