Radiosensibilité individuelle : les tests vont changer nos pratiques [Intrinsic radiosensitivity: predictive assays that will change the daily practice].

Details

Serval ID
serval:BIB_31527A9EF138
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Radiosensibilité individuelle : les tests vont changer nos pratiques [Intrinsic radiosensitivity: predictive assays that will change the daily practice].
Journal
Cancer Radiothérapie
Author(s)
Lacombe J., Riou O., Solassol J., Mangé A., Bourgier C., Fenoglietto P., Pèlegrin A., Ozsahin M., Azria D.
ISSN
1769-6658 (Electronic)
ISSN-L
1278-3218
Publication state
Published
Issued date
2013
Volume
17
Number
5-6
Pages
337-343
Language
french
Notes
Publication types: English Abstract ; Journal ArticlePublication Status: ppublish. pdf type: Mise au point
Abstract
The impact of curative radiotherapy depends mainly on the total dose delivered homogenously in the targeted volume. Nevertheless, the dose delivered to the surrounding healthy tissues may reduce the therapeutic ratio of many radiation treatments. In a same population treated in one center with the same technique, it appears that individual radiosensitivity clearly exists, namely in terms of late side effects that are in principle non-reversible. This review details the different radiobiological approaches that have been developed to better understand the mechanisms of radiation-induced late effects. We also present the possibilities of clinical use of predictive assays in the close future.
Pubmed
Web of science
Create date
21/11/2013 18:13
Last modification date
20/08/2019 13:16
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