The UniProtKB/Swiss-Prot Tox-Prot program: A central hub of integrated venom protein data.

Détails

ID Serval
serval:BIB_2F98F7136CEF
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
The UniProtKB/Swiss-Prot Tox-Prot program: A central hub of integrated venom protein data.
Périodique
Toxicon
Auteur(s)
Jungo F., Bougueleret L., Xenarios I., Poux S.
ISSN
1879-3150 (Electronic)
ISSN-L
0041-0101
Statut éditorial
Publié
Date de publication
2012
Volume
60
Numéro
4
Pages
551-557
Langue
anglais
Résumé
Animal toxins are of interest to a wide range of scientists, due to their numerous applications in pharmacology, neurology, hematology, medicine, and drug research. This, and to a lesser extent the development of new performing tools in transcriptomics and proteomics, has led to an increase in toxin discovery. In this context, providing publicly available data on animal toxins has become essential. The UniProtKB/Swiss-Prot Tox-Prot program (http://www.uniprot.org/program/Toxins) plays a crucial role by providing such an access to venom protein sequences and functions from all venomous species. This program has up to now curated more than 5000 venom proteins to the high-quality standards of UniProtKB/Swiss-Prot (release 2012_02). Proteins targeted by these toxins are also available in the knowledgebase. This paper describes in details the type of information provided by UniProtKB/Swiss-Prot for toxins, as well as the structured format of the knowledgebase.
Mots-clé
UniProtKB/Swiss-Prot Tox-Prot program, Database, Curation, Venom protein, Animal toxin, Bioinformatics
Pubmed
Web of science
Création de la notice
17/10/2012 10:09
Dernière modification de la notice
20/08/2019 13:14
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