The Impact of CAROtid plaque Screening on Smoking (CAROSS) cessation and control of other cardiovascular risk factors: rationale and design of a randomized controlled trial

Details

Serval ID
serval:BIB_2F7DCDA3126E
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
The Impact of CAROtid plaque Screening on Smoking (CAROSS) cessation and control of other cardiovascular risk factors: rationale and design of a randomized controlled trial
Journal
Contemporary clinical trials
Author(s)
Rodondi N., Bovet P., Hayoz D., Cornuz J.
ISSN
1559-2030[electronic]
Publication state
Published
Issued date
2008
Peer-reviewed
Oui
Volume
29
Number
5
Pages
767-773
Language
english
Abstract
BACKGROUND: Screening tests for subclinical cardiovascular disease, such as markers of atherosclerosis, are increasingly used in clinical prevention to identify individuals at high cardiovascular risk. Being aware of these test results might also enhance patient motivation to change unhealthy behaviors but the effectiveness of such a screening strategy has been poorly studied. METHODS: The CAROtid plaque Screening trial on Smoking cessation (CAROSS) is a randomized controlled trial in 530 regular smokers aged 40-70 years to test the hypothesis that carotid plaque screening will influence smokers' behavior with an increased rate of smoking cessation (primary outcome) and an improved control of other cardiovascular risk factors (secondary outcomes) after 1-year follow-up. All smokers will receive a brief advice for smoking cessation,and will subsequently be randomly assigned to either the intervention group (with plaques screening) or the control group (without plaque screening). Carotid ultrasound will be conducted with a standard protocol. Smokers with at least one carotid plaque will receive pictures of their own plaques with a structured explanation on the general significance of plaques. To ensure equal contact conditions, smokers not undergoing ultrasound and those without plaque will receive a relevant explanation on the risks associated with tobacco smoking. Study outcomes will be compared between smokers randomized to plaque screening and smokers not submitted to plaque screening. SUMMARY: This will be the first trial to assess the impact of carotid plaque screening on 1-year smoking cessation rates and levels of control of other cardiovascular risk factors.
Keywords
Adult, Aged, Cardiovascular Diseases, Cardiovascular Diseases/epidemiology, Cardiovascular Diseases/prevention & control, Carotid Arteries, Carotid Arteries/pathology, Carotid Arteries/ultrasonography, Female, Health Behavior, Humans, Male, Mass Screening, Middle Aged, Pilot Projects, Research Design, Risk Factors, Smoking, Smoking/prevention & control, Smoking Cessation
Pubmed
Web of science
Create date
03/03/2009 15:46
Last modification date
20/08/2019 13:13
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