Amyloïdose cardiaque: une maladie rare ? [Cardiac amyloidosis : a rare disease ?]

Détails

ID Serval
serval:BIB_2F7A12565706
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Amyloïdose cardiaque: une maladie rare ? [Cardiac amyloidosis : a rare disease ?]
Périodique
Revue medicale suisse
Auteur(s)
Hugelshofer S., N'koulou R., Monney P.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Statut éditorial
Publié
Date de publication
22/05/2019
Peer-reviewed
Oui
Volume
15
Numéro
652
Pages
1054-1059
Langue
français
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
Cardiac amyloidosis is an infiltrative cardiomyopathy, typically conducting to heart failure with preserved ejection fraction. There are several causes for the disease, from which two can already be seen in the young patient and are due to either genetic mutation or neoplasia. A third, non genetic cause, typically affects older patients (previously called senile amyloidosis) and appears to be much more prevalent than initially reported. A careful initial work-up and a high index of suspicion are important to detect as early as possible the disease, as it is associated with a poor prognosis in the late stage. A standardized diagnostic approach has been proposed with the use of bone scintigraphy, recently recognized as a sensitive diagnostic tool for this type of amyloidosis. With new disease modifying therapies recently becoming available, a more active diagnostic strategy is justified.
Mots-clé
Amyloidosis/diagnosis, Cardiomyopathies/diagnosis, Heart Failure, Humans, Rare Diseases
Pubmed
Création de la notice
25/05/2019 11:21
Dernière modification de la notice
20/08/2019 14:13
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