Dépression: le point sur les traitements psychopharma- cologiques [Pharmacotherapy of depression: recent developments]

Details

Serval ID
serval:BIB_2EEBAF4C185A
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Dépression: le point sur les traitements psychopharma- cologiques [Pharmacotherapy of depression: recent developments]
Journal
Revue medicale suisse
Author(s)
Baumann P.
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Publication state
Published
Issued date
19/09/2007
Peer-reviewed
Oui
Volume
3
Number
125
Pages
2079-2080,2083-2084
Language
french
Notes
Publication types: English Abstract ; Journal Article ; Review
Publication Status: ppublish
Abstract
The clinical properties of the first antidepressant, imipramine, were described already 50 years ago. Almost all antidepressants are noradrenergic, serotonergic and/or dopaminergic. Pharmaceutical companies experience difficulties in the development of drugs, of which the mecanism of action is related to other neuronal systems. Recently, the dual reuptake inhibitor duloxetine, the atypical antipsychotic quetiapine, desvenlafaxine (the main metabolite of venlafaxine) were developed for the treatment of depression. The noradrenergic and dopaminergic bupropion, in combination with other antidepressants, is a promising drug for the treatment of resistant depression. Finally, agomelatine, by its effects on the receptors of melatonin and on the 5-HT2c receptor, presents a unique pharmacological profile.
Keywords
Antidepressive Agents/pharmacology, Antidepressive Agents/therapeutic use, Depression/drug therapy, Drug Therapy, Combination, Humans
Pubmed
Create date
10/03/2008 10:37
Last modification date
04/05/2023 5:52
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