Characteristics of uterine contractility during menses in women with mild to moderate endometriosis
Details
Serval ID
serval:BIB_2C0D96678F73
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Characteristics of uterine contractility during menses in women with mild to moderate endometriosis
Journal
Fertility and Sterility
ISSN
0015-0282
Publication state
Published
Issued date
06/2002
Peer-reviewed
Oui
Volume
77
Number
6
Pages
1156-61
Notes
Journal Article --- Old month value: Jun
Abstract
OBJECTIVE: To establish the role of uterine contractions in retrograde menstruation with subsequent abdominal implantation of endometrial tissue. DESIGN: Controlled prospective study. SETTING: University hospital-based study. PATIENT(S): Infertile women with (n = 22) and without (n = 22) endometriosis. MAIN OUTCOME MEASURE(S): Frequency, amplitude, and basal pressure tone of uterine contractions; correlation of contractions with retrograde bleeding and presence of viable endometrial cells; and dysmenorrhea before and 3 and 24 months after surgery. RESULT(S): Compared with controls, patients with endometriosis had uterine contractions with higher frequency (22.73 +/- 5.66 osc/10 min vs. 11.09 +/- 3.26 osc/10 min), amplitude (20.83 +/- 3.94 mm Hg vs. 6.77 +/- 2.83 mm Hg), and basal pressure tone (50.14 +/- 16.30 mm Hg vs. 24.68 +/- 6.14 mm Hg). Dysmenorrhea was scored as 4.09 +/- 1.44 in patients with endometriosis and 0.86 +/- 1.42 in controls. Retrograde bleeding was found in 73% of patients with endometriosis vs. 9% of controls, and only 45% of patients with endometriosis had viable endometrial cells in the cul-de-sac. CONCLUSION(S): Endometriosis may result from abnormal myometrial contractility through tubal transportation, dissemination, and implantation of endometrial viable cells into the abdomen.
Keywords
Adult
Dysmenorrhea/epidemiology/etiology
Endometriosis/complications/pathology/*physiopathology
Endometrium/pathology
Female
Humans
Incidence
Menstruation/*physiology
Severity of Illness Index
Uterine Contraction/*physiology
Uterine Hemorrhage/etiology
Pubmed
Web of science
Create date
28/02/2008 12:37
Last modification date
20/08/2019 14:11