Article: article from journal or magazin.
Case report (case report): feedback on an observation with a short commentary.
Hemofiltration clearance of flecainide in a patient with acute renal failure
Intensive Care Medicine
Flecainide, a new antiarrhythmic drug, has been shown not no be removed to a significant extent by hemodialysis or peritoneal dialysis, in spite of a high renal clearance. Its systemic and hemofiltrate clearances, measured in a patient under continuous hemofiltration, were 402 and 19.7 ml/min respectively. The clearance ratio of less than 5% makes the contribution of hemofiltration to the elimination of flecainide clinically negligible.
*Flecainide/administration & dosage/pharmacokinetics *Hemofiltration Humans Kidney Failure, Acute/*therapy Male Middle Aged
Web of science
Last modification date