Evaluation of somatic cell variants deficient in glycosylphosphatidyl-inositol anchoring as candidates for genetic correction.

Détails

ID Serval
serval:BIB_2BA8D14627DF
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Evaluation of somatic cell variants deficient in glycosylphosphatidyl-inositol anchoring as candidates for genetic correction.
Périodique
Cell Biology International Reports
Auteur(s)
Fasel N., Déglon N., Rousseaux M., Beghdadi-Rais C., Bernard M., Bron C.
ISSN
0309-1651 (Print)
ISSN-L
0309-1651
Statut éditorial
Publié
Date de publication
1991
Volume
15
Numéro
11
Pages
1051-1064
Langue
anglais
Résumé
Many cell surface glycoproteins are anchored in the lipid bilayer by a glycosylphosphatidyl-inositol (GPI) structure. Recently, a number of cell lines which are deficient in the biosynthesis and/or addition of this anchor have been described. In this report, we summarize the current knowledge on these lines and discuss their potential use to isolate the genes involved in the GPI anchor biosynthetic pathway with a specific emphasis on L cell fibroblasts.
Mots-clé
Animals, Cell Line, Glycolipids/biosynthesis, Glycolipids/genetics, Glycosylphosphatidylinositols, Humans, Membrane Glycoproteins/metabolism, Phosphatidylinositols/biosynthesis, Phosphatidylinositols/genetics, Transfection, Tumor Cells, Cultured
Pubmed
Web of science
Création de la notice
24/01/2008 16:02
Dernière modification de la notice
03/03/2018 15:25
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