Evaluation of somatic cell variants deficient in glycosylphosphatidyl-inositol anchoring as candidates for genetic correction.
Details
Serval ID
serval:BIB_2BA8D14627DF
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Evaluation of somatic cell variants deficient in glycosylphosphatidyl-inositol anchoring as candidates for genetic correction.
Journal
Cell Biology International Reports
ISSN
0309-1651 (Print)
ISSN-L
0309-1651
Publication state
Published
Issued date
1991
Volume
15
Number
11
Pages
1051-1064
Language
english
Abstract
Many cell surface glycoproteins are anchored in the lipid bilayer by a glycosylphosphatidyl-inositol (GPI) structure. Recently, a number of cell lines which are deficient in the biosynthesis and/or addition of this anchor have been described. In this report, we summarize the current knowledge on these lines and discuss their potential use to isolate the genes involved in the GPI anchor biosynthetic pathway with a specific emphasis on L cell fibroblasts.
Keywords
Animals, Cell Line, Glycolipids/biosynthesis, Glycolipids/genetics, Glycosylphosphatidylinositols, Humans, Membrane Glycoproteins/metabolism, Phosphatidylinositols/biosynthesis, Phosphatidylinositols/genetics, Transfection, Tumor Cells, Cultured
Pubmed
Web of science
Create date
24/01/2008 15:02
Last modification date
20/08/2019 13:11
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