BUSCO: assessing genome assembly and annotation completeness with single-copy orthologs.
Details
State: Public
Version: Final published version
License: Not specified
Serval ID
serval:BIB_2B686A7F95A9
Type
Article: article from journal or magazin.
Publication sub-type
Minutes: analyse of a published work.
Collection
Publications
Institution
Title
BUSCO: assessing genome assembly and annotation completeness with single-copy orthologs.
Journal
Bioinformatics
ISSN
1367-4811 (Electronic)
ISSN-L
1367-4803
Publication state
Published
Issued date
2015
Peer-reviewed
Oui
Volume
31
Number
19
Pages
3210-3212
Language
english
Abstract
Genomics has revolutionized biological research, but quality assessment of the resulting assembled sequences is complicated and remains mostly limited to technical measures like N50.
We propose a measure for quantitative assessment of genome assembly and annotation completeness based on evolutionarily informed expectations of gene content. We implemented the assessment procedure in open-source software, with sets of Benchmarking Universal Single-Copy Orthologs, named BUSCO.
Software implemented in Python and datasets available for download from http://busco.ezlab.org.
evgeny.zdobnov@unige.ch
Supplementary data are available at Bioinformatics online.
We propose a measure for quantitative assessment of genome assembly and annotation completeness based on evolutionarily informed expectations of gene content. We implemented the assessment procedure in open-source software, with sets of Benchmarking Universal Single-Copy Orthologs, named BUSCO.
Software implemented in Python and datasets available for download from http://busco.ezlab.org.
evgeny.zdobnov@unige.ch
Supplementary data are available at Bioinformatics online.
Keywords
Animals, Computational Biology/methods, Gene Dosage/genetics, Genome, Genomics/methods, Humans, Molecular Sequence Annotation/methods, Software
Pubmed
Web of science
Open Access
Yes
Create date
20/09/2017 9:03
Last modification date
03/01/2020 18:03
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