BUSCO: assessing genome assembly and annotation completeness with single-copy orthologs.

Détails

ID Serval
serval:BIB_2B686A7F95A9
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
BUSCO: assessing genome assembly and annotation completeness with single-copy orthologs.
Périodique
Bioinformatics
Auteur(s)
Simão F.A., Waterhouse R.M., Ioannidis P., Kriventseva E.V., Zdobnov E.M.
ISSN
1367-4811 (Electronic)
ISSN-L
1367-4803
Statut éditorial
Publié
Date de publication
2015
Peer-reviewed
Oui
Volume
31
Numéro
19
Pages
3210-3212
Langue
anglais
Résumé
Genomics has revolutionized biological research, but quality assessment of the resulting assembled sequences is complicated and remains mostly limited to technical measures like N50.
We propose a measure for quantitative assessment of genome assembly and annotation completeness based on evolutionarily informed expectations of gene content. We implemented the assessment procedure in open-source software, with sets of Benchmarking Universal Single-Copy Orthologs, named BUSCO.
Software implemented in Python and datasets available for download from http://busco.ezlab.org.
evgeny.zdobnov@unige.ch
Supplementary data are available at Bioinformatics online.

Mots-clé
Animals, Computational Biology/methods, Gene Dosage/genetics, Genome, Genomics/methods, Humans, Molecular Sequence Annotation/methods, Software
Pubmed
Web of science
Open Access
Oui
Création de la notice
20/09/2017 10:03
Dernière modification de la notice
08/05/2019 16:20
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