Non-invasive detection of cocaine dissolved in wine bottles by (1) H magnetic resonance spectroscopy.

Détails

ID Serval
serval:BIB_2B21D7FA19BD
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Non-invasive detection of cocaine dissolved in wine bottles by (1) H magnetic resonance spectroscopy.
Périodique
Drug Testing and Analysis
Auteur(s)
Gambarota G., Perazzolo C., Leimgruber A., Meuli R., Mangin P., Augsburger M., Grabherr S.
ISSN
1942-7611 (Electronic)
Statut éditorial
Publié
Date de publication
2011
Volume
3
Numéro
9
Pages
544-547
Langue
anglais
Notes
Publication types: Journal Article
Résumé
Recently, a number of cases of smuggling dissolved cocaine in wine bottles have been reported. The aim of the present study was to determine whether cocaine dissolved in wine can be detected by proton magnetic resonance spectroscopy ((1) H MRS) on a standard clinical MR scanner, in intact (i.e. unopened) wine bottles. (1) H MRS experiments were performed with a 3 Tesla clinical scanner on wine phantoms with or without cocaine contamination. The aromatic protons of cocaine displayed resonance peaks in the 7-8 ppm region of the spectrum, where no overlapping resonances of wine were present. Additional cocaine resonances were detected in the 2-3 ppm region of the spectrum, between the resonances of ethanol and other wine constituents. Detection of cocaine in wine (at 5 mM, i.e. ∼1.5 g/L) was feasible in a scan time of 1 min. We conclude that dissolved cocaine can be detected in intact wine bottles, on a standard clinical MR scanner. Thus, (1) H MRS is the technique of choice to examine this type of suspicious cargo, since it allows for a non-destructive and rapid content characterization. Copyright © 2010 John Wiley & Sons, Ltd.
Pubmed
Création de la notice
06/12/2010 17:50
Dernière modification de la notice
29/05/2018 10:46
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