BUSCO applications from quality assessments to gene prediction and phylogenomics.

Détails

Ressource 1Télécharger: msx319.pdf (989.04 [Ko])
Etat: Serval
Version: Final published version
ID Serval
serval:BIB_2A4C7F8DA305
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
BUSCO applications from quality assessments to gene prediction and phylogenomics.
Périodique
Molecular biology and evolution
Auteur(s)
Waterhouse R.M., Seppey M., Simão F.A., Manni M., Ioannidis P., Klioutchnikov G., Kriventseva E.V., Zdobnov E.M.
ISSN
1537-1719 (Electronic)
ISSN-L
0737-4038
Statut éditorial
Publié
Date de publication
06/12/2017
Peer-reviewed
Oui
Pages
543-548
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: aheadofprint
Résumé
Genomics promises comprehensive surveying of genomes and metagenomes, but rapidly changing technologies and expanding data volumes make evaluation of completeness a challenging task. Technical sequencing quality metrics can be complemented by quantifying completeness of genomic datasets in terms of the expected gene content of Benchmarking Universal Single-Copy Orthologs (BUSCO, http://busco.ezlab.org). The latest software release implements a complete refactoring of the code to make it more flexible and extendable to facilitate high-throughput assessments. The original six lineage assessment datasets have been updated with improved species sampling, 34 new subsets have been built for vertebrates, arthropods, fungi, and prokaryotes that greatly enhance resolution, and datasets are now also available for nematodes, protists, and plants. Here we present BUSCO v3 with example analyses that highlight the wide-ranging utility of BUSCO assessments, which extend beyond quality control of genomics datasets to applications in comparative genomics analyses, gene predictor training, metagenomics, and phylogenomics.
Mots-clé
transcriptomics, metagenomics, bioinformatics, evolution, genomics
Pubmed
Web of science
Open Access
Oui
Création de la notice
16/12/2017 19:38
Dernière modification de la notice
08/05/2019 16:16
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