Infectious minor lymphocyte stimulating (Mls) antigens.

Details

Serval ID
serval:BIB_2A28C43D697E
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Infectious minor lymphocyte stimulating (Mls) antigens.
Journal
Seminars in Immunology
Author(s)
Acha-Orbea H., Waanders G.A., Shakhov A.N., Held W.
ISSN
1044-5323 (Print)
ISSN-L
1044-5323
Publication state
Published
Issued date
1992
Volume
4
Number
5
Pages
297-303
Language
english
Abstract
Minor lymphocyte stimulating (Mls) antigens have profound effects on the murine immune system and have been very important for our current understanding of immune tolerance. It has recently been discovered that these Mls antigens are encoded in an open reading frame located in the 3' long terminal repeat of endogenous and infectious mouse mammary tumor viruses (MMTV). In this review we will discuss the effects of a novel infectious MMTV with properties of Mls-1a on the neonatal and adult immune system in comparison to the effects of endogenous Mtv-7 (Mls-1a).
Keywords
Animals, Immune Tolerance, Mammary Tumor Virus, Mouse/immunology, Mammary Tumor Virus, Mouse/pathogenicity, Mice, Mice, Inbred BALB C, Mice, Nude, Minor Lymphocyte Stimulatory Antigens/immunology
Pubmed
Create date
17/01/2008 15:24
Last modification date
20/08/2019 13:09
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