Article: article from journal or magazin.
Endocrine pancreatic tumours: which are the most useful MRI sequences?
1432-1084 (Electronic)0938-7994 (Linking)
Caramella, CDromain, CDe Baere, TBoulet, BSchlumberger, MDucreux, MBaudin, EengGermany2010/07/30 06:00Eur Radiol. 2010 Nov;20(11):2618-27. doi: 10.1007/s00330-010-1840-5. Epub 2010 Jul 29.
OBJECTIVES: To determine magnetic resonance imaging (MRI) signal and enhancement characteristics of endocrine pancreatic tumours (ETPs) and which MR sequences show them most consistently. METHODS: Fifty-five consecutive patients with 68 ETPs underwent 1.5-T abdominal MRI comprising T2-weighted, unenhanced T1-weighted and dynamic T1-weighted after injection of gadopentetate dimeglumine sequences. Twenty-one patients underwent diffusion-weighted imaging (DWI). Two radiologists identified the number, location, size, signal and enhancement patterns of ETPs, and determined a confidence scale indicating the presence of tumours on DWI. The results were compared with echo-endoscopy (endoscopic ultrasound) findings. RESULTS: The detection sensitivity was 95%, similar to that of echo-endoscopy. T2-weighted and T1-weighted sequences at the arterial phase had the highest contrast-to-noise ratio (CNR) median value. On DWI, the mean sensitivity was 65%. The mean apparent diffusion coefficient (ADC) value of ETP was significantly lower than in the normal parenchyma. CONCLUSION: In suspected ETP, MRI is a sensitive method, similar to echo-endoscopy and could be recommended as the first imaging technique. T2-weighted sequences and T1-weighted sequences in the arterial phase are the optimal pulse sequences. The quantitative assessment of ADC values is a promising tool for the characterisation of pancreatic lesions.
Adult, Aged, Contrast Media, Diffusion Magnetic Resonance Imaging, Endosonography, Female, Gadolinium DTPA, Humans, *Magnetic Resonance Imaging, Male, Middle Aged, Pancreas/pathology/ultrasonography, Pancreatic Neoplasms/*diagnosis/ultrasonography, Sensitivity and Specificity
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