Thrombose des sinus veineux cerebraux dans la maladie de Behcet: description d'un cas et revue de la literature. [Cerebral sinus thrombosis in Behcet disease: case report and review of the literature]

Details

Serval ID
serval:BIB_290407CED3B0
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Thrombose des sinus veineux cerebraux dans la maladie de Behcet: description d'un cas et revue de la literature. [Cerebral sinus thrombosis in Behcet disease: case report and review of the literature]
Journal
Klinische Monatsblatter fur Augenheilkunde
Author(s)
Chaloupka  K., Baglivo  E., Hofer  M., Chizzolini  C., Delavelle  J., Rossillion  B., Safran  A. B.
ISSN
0023-2165
Publication state
Published
Issued date
03/2003
Peer-reviewed
Oui
Volume
220
Number
3
Pages
186-8
Notes
Case Reports
English Abstract
Journal Article --- Old month value: Mar
Abstract
BACKGROUND: Behcet's disease is a chronic inflammatory disorder, clinically characterised by multisystemic vasculitis. Primary neurologic involvement in childhood is quite exceptional. We report a case of a child with recurrent venous thrombosis of the dural sinus. Behcet's disease was diagnosed. HISTORY AND SIGNS: A 13-year-old boy from Eritrea was referred to our clinic with severe headaches and photophobia one month after onset. Ophthalmological examination disclosed a bilateral papilledema. Recurrent oral ulcers and pseudo-folliculitis were present. Pathergy test was positive. THERAPY AND OUTCOME: Complementary investigations disclosed an inflammatory syndrome. Computertomography was normal. Cranial magnetic resonance venography disclosed multiple cerebral sinus thrombosis (superior sagittal sinus, sigmoid sinus and lateral left sinus). There was no evidence of infectious, inflammatory or hypercoagulation disorder. A Behcet's disease was diagnosed based on the medical history and clinical examination. Whilst his general health deteriorated rapidly before treatment, he improved quickly after the onset of therapy with immunosuppression (Prednisone and Ciclosporine) in combination with anticoagulation (coumarin/Sintrom). CONCLUSION: Behcet's disease is uncommon and difficult to diagnose in children. Neurologic involvement as a first presentation is rarely described, but might be underestimated. We emphasise, therefore, the systematic application of magnetic resonance venography in children with unclear persistent headaches.
Keywords
Adolescent Anticoagulants/administration & dosage Behcet Syndrome/complications/*diagnosis/drug therapy Cyclosporine/administration & dosage Diagnosis, Differential Drug Therapy, Combination Fluorescein Angiography Follow-Up Studies Humans Immunosuppressive Agents/administration & dosage Magnetic Resonance Angiography Male Prednisone/administration & dosage Sinus Thrombosis, Intracranial/*diagnosis/drug therapy/etiology
Pubmed
Web of science
Create date
20/01/2008 15:23
Last modification date
20/08/2019 13:08
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