Great future or greedy venture: Precision medicine needs philosophy.

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State: Public
Version: Final published version
License: CC BY-NC 4.0
Serval ID
serval:BIB_28C3E384BE78
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Great future or greedy venture: Precision medicine needs philosophy.
Journal
Health science reports
Author(s)
Jiao F., Guo R., Beckmann J.S., Yan Z., Yang Y., Hu J., Wang X., Xie S.
ISSN
2398-8835 (Electronic)
ISSN-L
2398-8835
Publication state
Published
Issued date
09/2021
Peer-reviewed
Oui
Volume
4
Number
3
Pages
e376
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: epublish
Abstract
Over the past decade, we have witnessed the initiation and implementation of precision medicine (PM), a discipline that promises to individualize and personalize medical management and treatment, rendering them ultimately more precise and effective. Despite of the continuing advances and numerous clinical applications, the potential of PM remains highly controversial, sparking heated debates about its future.
The present article reviews the philosophical issues and practical challenges that are critical to the feasibility and implementation of PM.
The explanation and argument about the relations between PM and computability, uncertainty as well as complexity, show that key foundational assumptions of PM might not be fully validated.
The present analysis suggests that our current understanding of PM is probably oversimplified and too superficial. More efforts are needed to realize the hope that PM has elicited, rather than make the term just as a hype.
Keywords
biomarker, cancer, data, model, precision medicine, system
Pubmed
Web of science
Open Access
Yes
Create date
27/09/2021 11:40
Last modification date
23/11/2022 8:09
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