PTX3 Polymorphisms and Invasive Mold Infections After Solid Organ Transplant.

Wójtowicz, A.; Lecompte, T.D.; Bibert, S.; Manuel, O.; Rüeger, S.; Berger, C.; Boggian, K.; Cusini, A.; Garzoni, C.; Hirsch, H.; Khanna, N.; Mueller, N.J.; Meylan, P.R.; Pascual, M.; van Delden, C.; Bochud, P.Y.

doi:10.1093/cid/civ386

PTX3 Polymorphisms and Invasive Mold Infections After Solid Organ Transplant.

Details

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UNIL restricted access
State: Public
Version: Final published version
License: All rights reserved

Serval ID

serval:BIB_2869E1CA81A7

Type

Article: article from journal or magazin.

Collection

Publications

Institution

UNIL/CHUV

Title

PTX3 Polymorphisms and Invasive Mold Infections After Solid Organ Transplant.

Journal

Clinical infectious diseases

Author(s)

Wójtowicz A., Lecompte T.D., Bibert S., Manuel O., Rüeger S., Berger C., Boggian K., Cusini A., Garzoni C., Hirsch H., Khanna N., Mueller N.J., Meylan P.R., Pascual M., van Delden C., Bochud P.Y.

Working group(s)

Swiss Transplant Cohort Study

Contributor(s)

Achermann R., Aubert J.D., Baumann P., Beldi G., Benden C., Berger C., Binet I., Bochud P.Y., Boely E., Bucher H., Bühler L., Carell T., Catana E., Chalandon Y., de Geest S., de Rougemont O., Dickenmann M., Duchosal M., Fehr T., Ferrari-Lacraz S., Garzoni C., Gasche Y., Soccal P.G., Giostra E., Golshayan D., Good D., Hadaya K., Hess C., Hillinger S., Hirsch H.H., Hofbauer G., Huynh-Do U., Immer F., Klaghofer R., Koller M., Kuntzen T., Laesser B., Lehmann R., Lovis C., Manuel O., Marti H.P., Martin P.Y., Meylan P., Mohacsi P., Morard I., Morel P., Mueller U., Mueller N.J., Mueller-McKenna H., Müller T., Müllhaupt B., Nadal D., Nair G., Pascual M., Passweg J., Ziegler C.P., Rick J., Roosnek E., Rosselet A., Rothlin S., Ruschitzka F., Schanz U., Schaub S., Seiler C., Semmo N., Stampf S., Steiger J., Toso C., Tsinalis D., Van Delden C., Venetz J.P., Villard J., Wick M., Wilhelm M., Yerly P.

ISSN

1537-6591 (Electronic)

ISSN-L

1058-4838

Publication state

Published

Issued date

15/08/2015

Peer-reviewed

Oui

Volume

Number

Pages

619-622

Language

english

Notes

Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish

Abstract

Donor PTX3 polymorphisms were shown to influence the risk of invasive aspergillosis among hematopoietic stem cell transplant recipients. Here, we show that PTX3 polymorphisms are independent risk factors for invasive mold infections among 1101 solid organ transplant recipients, thereby strengthening their role in mold infection pathogenesis and patients' risk stratification.

Keywords

C-Reactive Protein/genetics, Female, Fungi/isolation & purification, Humans, Immunocompromised Host, Male, Mycoses/genetics, Mycoses/immunology, Organ Transplantation/adverse effects, Polymorphism, Genetic, Prospective Studies, Serum Amyloid P-Component/genetics, PTX3, SNP, genetic susceptibility, innate immunity, solid organ transplant

URN

urn:nbn:ch:serval-BIB_2869E1CA81A72

OAI-PMH

oai:serval.unil.ch:BIB_2869E1CA81A7

DOI

10.1093/cid/civ386

Pubmed

25977268

Web of science

000359344200021

Open Access

Yes