Virtual versus true non-contrast dual-energy CT imaging for the diagnosis of aortic intramural hematoma.

Détails

ID Serval
serval:BIB_2863FDB5AF98
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Virtual versus true non-contrast dual-energy CT imaging for the diagnosis of aortic intramural hematoma.
Périodique
European radiology
Auteur(s)
Si-Mohamed S., Dupuis N., Tatard-Leitman V., Rotzinger D., Boccalini S., Dion M., Vlassenbroek A., Coulon P., Yagil Y., Shapira N., Douek P., Boussel L.
ISSN
1432-1084 (Electronic)
ISSN-L
0938-7994
Statut éditorial
Publié
Date de publication
01/07/2019
Peer-reviewed
Oui
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: aheadofprint
Résumé
To assess whether virtual non-contrast (VNC) images derived from contrast dual-layer dual-energy computed tomography (DL-DECT) images could replace true non-contrast (TNC) images for aortic intramural hematoma (IMH) diagnosis in acute aortic syndrome (AAS) imaging protocols by performing quantitative as well as qualitative phantom and clinical studies.
Patients with confirmed IMH were included retrospectively in two centers. For in vitro imaging, a custom-made phantom of IMH was placed in a semi-anthropomorphic thorax phantom (QRM GmbH) and imaged on a DL-DECT at 120 kVp under various conditions of patient size, radiation exposure, and reconstruction modes. For in vivo imaging, 21 patients (70 ± 13 years) who underwent AAS imaging protocols at 120 kVp were included. In both studies, contrast-to-noise ratio (CNR) between hematoma and lumen was compared using a paired t test. Diagnostic confidence (1 = non-diagnostic, 4 = exemplary) for VNC and TNC images was rated by two radiologists and compared. Effective radiation doses for each acquisition were calculated.
In both the phantom and clinical studies, we observed that the CNRs were similar between the VNC and TNC images. Moreover, both methods allowed differentiating the hyper-attenuation within the hematoma from the blood. Finally, we obtained equivalent high diagnostic confidence with both VNC and TNC images (VNC = 3.2 ± 0.7, TNC = 3.1 ± 0.7; p = 0.3). Finally, by suppressing TNC acquisition and using VNC, the mean effective dose reduction would be 40%.
DL-DECT offers similar performances with VNC and TNC images for IMH diagnosis without compromise in diagnostic image quality.
• Dual-layer dual-energy CT enables virtual non-contrast imaging from a contrast-enhanced acquisition. • Virtual non-contrast imaging with dual-layer dual-energy CT reduces the number of acquisitions and radiation exposure in acute aortic syndrome imaging protocol. • Dual-layer dual-energy CT has the potential to become a suitable imaging tool for acute aortic syndrome.
Mots-clé
Radiology Nuclear Medicine and imaging, General Medicine, Acute disease, Aorta, Humans, In vitro, Tomography, x-ray computed
Pubmed
Création de la notice
02/07/2019 14:44
Dernière modification de la notice
21/08/2019 6:33
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