Imaging of congenital Zika virus infection: the route to identification of prognostic factors.

Détails

ID Serval
serval:BIB_276BE38DEDF1
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Imaging of congenital Zika virus infection: the route to identification of prognostic factors.
Périodique
Prenatal Diagnosis
Auteur(s)
Vouga M., Baud D.
ISSN
1097-0223 (Electronic)
ISSN-L
0197-3851
Statut éditorial
Publié
Date de publication
2016
Peer-reviewed
Oui
Volume
36
Numéro
9
Pages
799-811
Langue
anglais
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Résumé
Zika virus (ZIKV) has recently emerged as a novel teratogenic agent associated with severe neurological complications. The risk associated with maternal infection remains to be exactly defined but appears to be significant. Like other TORCH agents (toxoplasmosis, other agents, rubella, cytomegalovirus and herpes simplex), it is unlikely that all affected fetuses will be symptomatic at birth. It is therefore urgent to better define the spectrum of anomalies observed in infected fetuses to provide adequate parental counseling. In this review, we provide a comprehensive analysis of major cases described to date and highlight specific prenatal and postnatal radiological findings of congenital ZIKV infection. A total of 19 reports were included in our analysis. ZIKV seemed to harbor a specific tropism for the central nervous system, and anomalies were mostly limited to the brain. Major radiological findings were ventriculomegaly, diffuse calcifications and signs of abnormal gyration as well as cortical development. In addition, a significant number of fetuses suffered from intra uterine growth restriction. Based on these findings, we provide recommendations for adequate radiological monitoring of at-risk pregnancies. © 2016 John Wiley & Sons, Ltd.
Pubmed
Web of science
Open Access
Oui
Création de la notice
04/08/2016 17:07
Dernière modification de la notice
20/08/2019 13:06
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