Article: article from journal or magazin.
Case report (case report): feedback on an observation with a short commentary.
Frosted branch angiitis with undiagnosed Hodgkin lymphoma.
European Journal of Ophthalmology
PURPOSE: To report the case of a patient with bilateral frosted branch angiitis and undiagnosed Hodgkin lymphoma. METHODS: Review of clinical history, laboratory findings, histology of supraclavicular lymph node biopsy, and follow-up. RESULTS: A 22-year-old man presented with a sudden, bilateral visual loss. Fundus examination and fluorescein angiography disclosed a bilateral frosted branch angiitis that was dramatically responsive to systemic corticosteroid therapy. Laboratory tests were unremarkable but radiologic studies showed extensive mediastinal and supraclavicular lymphadenopathy. A supraclavicular lymph node biopsy led to the diagnosis of nodular sclerosis Hodgkin lymphoma. CONCLUSIONS: The occurrence of frosted branch angiitis in combination with classical Hodgkin lymphoma, although possibly coincidental, raises the possibility of a paraneoplastic syndrome. Thus, we suggest that, for patients with frosted branch angiitis, Hodgkin lymphoma should be considered in the diagnostic workup.
Administration, Oral, Biopsy, Fluorescein Angiography, Glucocorticoids/therapeutic use, Hodgkin Disease/diagnosis, Humans, Infusions, Intravenous, Lymph Nodes/pathology, Male, Methylprednisolone/therapeutic use, Retinal Vasculitis/diagnosis, Visual Acuity, Young Adult
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