Jejunal Occlusion Caused by Heterotopic Gastric and Duodenal Mucosa: A Late Complication of a Complex Intestinal Malformation.

Details

Serval ID
serval:BIB_25D754E4CAC7
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Title
Jejunal Occlusion Caused by Heterotopic Gastric and Duodenal Mucosa: A Late Complication of a Complex Intestinal Malformation.
Journal
International journal of surgical pathology
Author(s)
Seyde O., Puppa G., Morel P., Wildhaber B.E., Rougemont A.L.
ISSN
1940-2465 (Electronic)
ISSN-L
1066-8969
Publication state
Published
Issued date
08/2017
Peer-reviewed
Oui
Volume
25
Number
5
Pages
453-457
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
We report a rare case of late complication of a complex intestinal malformation. At day 1 of life, a baby girl underwent resection of an atretic jejunal segment, associated with an enteric duplication harboring foci of gastric and duodenal heterotopia. After an asymptomatic period of 19 years, the patient presented with acute bowel obstruction. Recurrence of the jejunal occlusion at the previous anastomotic site was caused by mucosa hyperplasia in association with heterotopic gastric and duodenal tissue. A Wnt/β-catenin pathway deregulation was hypothesized but not confirmed by CTNNB1 exon 3 mutation analysis. This case illustrates a rare association of 3 pathologies-namely, intestinal atresia, enteric duplication, and heterotopia, with a late-occurring acute complication.

Keywords
ectopia, gastrointestinal tract duplication, intestinal atresia, β-catenin
Pubmed
Web of science
Create date
22/01/2018 11:29
Last modification date
20/08/2019 13:04
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