Outcome of treatment of pulmonary tuberculosis in Switzerland in 1996.

Détails

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Etat: Public
Version: Final published version
ID Serval
serval:BIB_24370
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Outcome of treatment of pulmonary tuberculosis in Switzerland in 1996.
Périodique
Swiss medical weekly
Auteur(s)
Helbling P., Medinger C., Altpeter E., Raeber P.A., Beeli D., Zellweger J.P.
ISSN
1424-7860 (Print)
ISSN-L
0036-7672
Statut éditorial
Publié
Date de publication
07/09/2002
Peer-reviewed
Oui
Volume
132
Numéro
35-36
Pages
517-522
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
Adequate treatment of pulmonary tuberculosis cures patients and reduces transmission. The study assesses treatment outcomes under current conditions in Switzerland.
Retrospective cohort study including all TB cases with positive sputum cultures notified to the national surveillance system between July 1996 and June 1997. Ten months after notification, treating physicians reported the outcomes using WHO categories.
Of 265 patients, 209 (79%) completed at least 6 months' treatment, 3 (1%) were treatment failures, 23 (9%) died, 8 (3%) defaulted from treatment and 22 (8%) left the country. The proportion of successful treatments did not significantly differ between the 103 Swiss-born (80%) and the 162 foreign-born (78%) patients. There were 19 deaths (18%) in the Swiss-born and 4 (2%) in the foreign-born groups; death was caused by TB in two patients, 10 died of other causes (cause unknown in 11). In the foreign-born group there were 31 (19%) potentially unsatisfactory outcomes (treatment failure, default from treatment, transfer abroad) and in the Swiss-born group 2 (2%). Default from treatment involved 8 patients, 6 of whom were asylum seekers. In a multivariate analysis potentially unsatisfactory outcomes were not significantly associated with foreign origin but with status as a foreigner of irregular or unknown legal status (adj. OR 8.8; 95% CI 1.4 to 53.7).
Overall treatment success rates are satisfactory and similar to those of other western European countries. Potentially unsatisfactory outcomes are more common in foreign-born persons of irregular legal status. Tracking of non-adherent patients by health workers could further improve outcomes.

Mots-clé
Adolescent, Adult, Age Distribution, Aged, Aged, 80 and over, Antitubercular Agents/therapeutic use, Child, Child, Preschool, Confidence Intervals, Female, Health Care Surveys, Humans, Incidence, Male, Middle Aged, Odds Ratio, Outcome Assessment (Health Care), Prognosis, Retrospective Studies, Risk Factors, Sex Distribution, Survival Rate, Switzerland/epidemiology, Treatment Outcome, Tuberculosis, Pulmonary/diagnosis, Tuberculosis, Pulmonary/drug therapy, Tuberculosis, Pulmonary/epidemiology
Pubmed
Web of science
Création de la notice
19/11/2007 12:20
Dernière modification de la notice
20/08/2019 13:02
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