A review of the role of mechanical forces in cutaneous wound healing.

Details

Serval ID
serval:BIB_2402BD9E564F
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Title
A review of the role of mechanical forces in cutaneous wound healing.
Journal
The Journal of surgical research
Author(s)
Agha R., Ogawa R., Pietramaggiori G., Orgill D.P.
ISSN
1095-8673 (Electronic)
ISSN-L
0022-4804
Publication state
Published
Issued date
12/2011
Peer-reviewed
Oui
Volume
171
Number
2
Pages
700-708
Language
english
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Abstract
Cutaneous wound healing is a complex process with many types of mechanical forces regulating the quality and speed of healing. The role of mechanical forces in regulating tissue growth, repair and remodelling was recognised more than a century ago. Such forces influence gene expression, the synthesis of growth factors and inflammatory mediators and cellular processes like proliferation of many load-sensitive cells. However, the exact mechanisms by which these forces interact with cells and ways to use them to stimulate tissues are still active research fronts. This article sets to review the literature on mechanical forces and their role in cutaneous wound healing.

Keywords
Animals, Humans, Keloid/physiopathology, Neovascularization, Physiologic/physiology, Skin/blood supply, Skin/injuries, Skin Physiological Phenomena, Stress, Mechanical, Wound Healing/physiology
Pubmed
Web of science
Create date
16/01/2018 16:11
Last modification date
20/08/2019 14:01
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