Echocardiographic and invasive measurements of pulmonary artery pressure correlate closely at high altitude.

Détails

ID Serval
serval:BIB_23AF74838198
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Echocardiographic and invasive measurements of pulmonary artery pressure correlate closely at high altitude.
Périodique
American Journal of Physiology. Heart and Circulatory Physiology
Auteur(s)
Allemann Y., Sartori C., Lepori M., Pierre S., Mélot C., Naeije R., Scherrer U., Maggiorini M.
ISSN
0363-6135
Statut éditorial
Publié
Date de publication
2000
Peer-reviewed
Oui
Volume
279
Numéro
4
Pages
H2013-2016
Langue
anglais
Notes
Publication types: Journal Article
Résumé
Exaggerated hypoxia-induced pulmonary hypertension is a hallmark of high-altitude pulmonary edema (HAPE) and plays a major role in its pathogenesis. Many studies of HAPE have estimated systolic pulmonary arterial pressure (SPAP) with Doppler echocardiography. Whereas at low altitude, Doppler echocardiographic estimation of SPAP correlates closely with its invasive measurement, no such evidence exists for estimations obtained at high altitude, where alterations of blood viscosity may invalidate the simplified Bernoulli equation. We measured SPAP by Doppler echocardiography and invasively in 14 mountaineers prone to HAPE and in 14 mountaineers resistant to this condition at 4,559 m. Mountaineers prone to HAPE had more pronounced pulmonary hypertension (57 +/- 12 and 58 +/- 10 mmHg for noninvasive and invasive determination, respectively; means +/- SD) than subjects resistant to HAPE (37 +/- 8 and 37 +/- 6 mmHg, respectively), and the values measured in the two groups as a whole covered a wide range of pulmonary arterial pressures (30-83 mmHg). Spearman test showed a highly significant correlation (r = 0.89, P < 0.0001) between estimated and invasively measured SPAP values. The mean difference between invasively measured and Doppler-estimated SPAP was 0.5 +/- 8 mmHg. At high altitude, estimation of SPAP by Doppler echocardiography is an accurate and reproducible method that correlates closely with its invasive measurement.
Mots-clé
Adult, Altitude, Blood Pressure/physiology, Blood Pressure Determination/methods, Disease Susceptibility, Echocardiography, Female, Humans, Male, Mountaineering, Pulmonary Artery/physiology, Pulmonary Artery/ultrasonography, Pulmonary Edema/etiology, Systole
Pubmed
Web of science
Création de la notice
22/02/2008 16:02
Dernière modification de la notice
03/03/2018 14:55
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