Risk factors for positive tuberculin skin tests among migrant and resident children in Lausanne, Switzerland.

Détails

Ressource 1Télécharger: 16511706.pdf (621.09 [Ko])
Etat: Serval
Version: Final published version
ID Serval
serval:BIB_23A3C9361276
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Risk factors for positive tuberculin skin tests among migrant and resident children in Lausanne, Switzerland.
Périodique
Swiss Medical Weekly
Auteur(s)
Collet E., Krahenbuhl J.D., Gehri M., Bissery A., Zellweger J.P.
ISSN
1424-7860
Statut éditorial
Publié
Date de publication
2005
Peer-reviewed
Oui
Volume
135
Numéro
47-48
Pages
703-709
Langue
anglais
Résumé
SETTING: Ambulatory paediatric clinic in Lausanne, Switzerland, a country with a significant proportion of tuberculosis (TB) among immigrants. AIM: To assess the factors associated with positive tuberculin skin tests (TST) among children examined during a health check-up or during TB contact tracing, notably the influence of BCG vaccination (Bacille Calmette Guérin) and history of TB contact. METHOD: A descriptive study of children who had a TST (2 Units RT23) between November 2002 and April 2004. Age, sex, history of TB contact, BCG vaccination status, country of origin and birth outside Switzerland were recorded. RESULTS: Of 234 children, 176 (75%) had a reaction equal to zero and 31 (13%) tested positive (>10 mm). In a linear regression model, the size of the TST varied significantly according to the history of TB contact, age, TB incidence in the country of origin and BCG vaccination status but not according to sex or birth in or outside Switzerland. In a logistic regression model including all the recorded variables, age (Odds Ratio = 1.21, 95% CI 1.08; 1.35), a history of TB contact (OR = 7.31, 95% CI 2.23; 24) and the incidence of TB in the country of origin (OR = 1.01, 95% CI 1.00; 1.02) were significantly associated with a positive TST but sex (OR = 1.18, 95% CI 0.50; 2.78) and BCG vaccination status (OR = 2.97, 95% CI 0.91; 9.72) were not associated. CONCLUSIONS: TB incidence in the country of origin, BCG vaccination and age influence the TSTreaction (size or proportion of TST > or = 10 mm). However the most obvious risk factor for a positive TST is a history of contact with TB.
Mots-clé
Adolescent, Age Distribution, BCG Vaccine, Child, Child, Preschool, Female, Follow-Up Studies, Humans, Incidence, Infant, Infant, Newborn, Male, Regression Analysis, Risk Factors, Sensitivity and Specificity, Switzerland, Transients and Migrants, Tuberculin Test, Tuberculosis
Pubmed
Web of science
Création de la notice
25/01/2008 11:09
Dernière modification de la notice
11/06/2018 12:50
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