Extensive local adaptation within the chemosensory system following Drosophila melanogaster's global expansion.

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Ressource 1Télécharger: ncomms11855.pdf (1140.94 [Ko])
Etat: Public
Version: Final published version
ID Serval
serval:BIB_237C31A1A8A9
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Extensive local adaptation within the chemosensory system following Drosophila melanogaster's global expansion.
Périodique
Nature Communications
Auteur(s)
Arguello J.R., Cardoso-Moreira M., Grenier J.K., Gottipati S., Clark A.G., Benton R.
ISSN
2041-1723 (Electronic)
ISSN-L
2041-1723
Statut éditorial
Publié
Date de publication
2016
Volume
7
Pages
ncomms11855
Langue
anglais
Notes
Publication types: Journal ArticlePublication Status: epublish
Résumé
How organisms adapt to new environments is of fundamental biological interest, but poorly understood at the genetic level. Chemosensory systems provide attractive models to address this problem, because they lie between external environmental signals and internal physiological responses. To investigate how selection has shaped the well-characterized chemosensory system of Drosophila melanogaster, we have analysed genome-wide data from five diverse populations. By couching population genomic analyses of chemosensory protein families within parallel analyses of other large families, we demonstrate that chemosensory proteins are not outliers for adaptive divergence between species. However, chemosensory families often display the strongest genome-wide signals of recent selection within D. melanogaster. We show that recent adaptation has operated almost exclusively on standing variation, and that patterns of adaptive mutations predict diverse effects on protein function. Finally, we provide evidence that chemosensory proteins have experienced relaxed constraint, and argue that this has been important for their rapid adaptation over short timescales.
Pubmed
Web of science
Open Access
Oui
Création de la notice
08/07/2016 8:57
Dernière modification de la notice
20/08/2019 13:01
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