Article: article from journal or magazin.
Autoregulation du débit sanguin du nerf optique chez l'homme [Autoregulation in ischemia of the optic nerve in the human]
Klinische Monatsblätter für Augenheilkunde
Publication types: English Abstract ; Journal Article ; Research Support, Non-U.S. Gov't
BACKGROUND: Autoregulation is defined as the maintenance of constant blood flow in a vascular system in spite of changes in perfusion pressure (PPm). MATERIALS AND METHODS: PPm was decreased by increasing the intraocular pressure (IOP) with a suction cup and optic nerve blood flow was measured with the laser Doppler flowmetry technique (LDF) in 9 normal volunteers. RESULTS: The blood flow was autoregulated down to a PPm of 13 mm Hg (IOP = 47 mm Hg). CONCLUSIONS: These results confirm previous studies in cats and monkeys. The mechanism of autoregulation is probably a decrease in resistance due to capillary recruitment.
Adult, Capillary Resistance/physiology, Homeostasis/physiology, Humans, Intraocular Pressure/physiology, Ischemia/physiopathology, Laser-Doppler Flowmetry, Male, Middle Aged, Optic Nerve/blood supply, Reference Values
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