Article: article from journal or magazin.
Strategy to tether organometallic ruthenium-arene anticancer compounds to recombinant human serum albumin
PT - Journal Article PT - Research Support, Non-U.S. Gov't
In order to utilize macromolecules for drug targeting and delivery, a strategy to tether organometallic ruthenium-arene drugs to carrier protein molecules was developed. The approach involves the design of a drug fragment capable of conjugating to linker molecules on a modified carrier protein via hydrazone bond formation. The proof-of-concept using recombinant human serum albumin is described
Antineoplastic Agents/chemistry/Humans/Organometallic Compounds/Proteins/Recombinant Proteins/Research/Ruthenium/Science/Serum Albumin/Switzerland
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