Role of the Endocytosis of Caveolae in Intracellular Signaling and Metabolism.

Details

Serval ID
serval:BIB_2226864B6107
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Role of the Endocytosis of Caveolae in Intracellular Signaling and Metabolism.
Journal
Progress in molecular and subcellular biology
Author(s)
Muriel O., Sánchez-Álvarez M., Strippoli R., Del Pozo M.A.
ISSN
0079-6484 (Print)
ISSN-L
0079-6484
Publication state
Published
Issued date
2018
Peer-reviewed
Oui
Volume
57
Pages
203-234
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Abstract
Caveolae are 60-80 nm invaginated plasma membrane (PM) nanodomains, with a specific lipid and protein composition, which assist and regulate multiple processes in the plasma membrane-ranging from the organization of signalling complexes to the mechanical adaptation to changes in PM tension. However, since their initial descriptions, these structures have additionally been found tightly linked to internalization processes, mechanoadaptation, to the regulation of signalling events and of endosomal trafficking. Here, we review caveolae biology from this perspective, and its implications for cell physiology and disease.
Keywords
Animals, Caveolae/metabolism, Cell Membrane/genetics, Cell Membrane/metabolism, Endocytosis/genetics, Humans, Metabolic Networks and Pathways/genetics, Protein Transport/genetics, Signal Transduction/genetics
Pubmed
Web of science
Create date
20/08/2018 14:58
Last modification date
20/08/2019 12:59
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