Long term results of multimodality treatment of craniopharyngioma in children.

Details

Serval ID
serval:BIB_22075DFFC961
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Long term results of multimodality treatment of craniopharyngioma in children.
Journal
Journal of Clinical Neuroscience
Author(s)
Vernet O., Montes J.L., Farmer J.P., Blundell J.E., Bertrand G., Freeman C.R.
ISSN
1532-2653 (Electronic)
ISSN-L
0967-5868
Publication state
Published
Issued date
05/1999
Volume
6
Number
3
Pages
199-203
Language
english
Notes
Publication types: JOURNAL ARTICLE ; JOURNAL ARTICLE
Publication Status: ppublish
Abstract
The management of craniopharyngioma has been controversial for years. We review our 20 year experience in the treatment of paediatric craniopharyngioma. Twenty-five patients were treated for craniopharyngioma at The Montreal Children's Hospital from 1972 to 1991. They included 15 males and 10 females whose median age was 10 years. The initial clinical manifestations were remarkable for a predominance of symptoms and signs related to intracranial hypertension, followed in frequency by visual and endocrinological deficits. Radiologically, there were five cystic craniopharyngiomas, one solid and 19 mixed. Several therapeutic approaches were used including stereotactic drainage followed by radiotherapy or radiosurgery (three cases), transsphenoidal removal (six cases) and subfrontal and/or pterional craniotomy for total (three cases) or partial (13 cases) removal, followed by radiotherapy in 10 cases. The follow up period averaged 11 years. Eight patients recurred, three after total and three after partial removal; none of these six patients had received radiotherapy. Two cases treated by stereotactic drainage recurred, one received adjuvant radiosurgery and the other conventional radiotherapy. Morbidity was lower, and quality of survival better, with more conservative approaches. More conservative approaches in the management of craniopharyngioma are reasonable alternatives for treatment. Similar rates of disease control are observed with less morbidity and better quality of survival. Copyright 1999 Harcourt Publishers Ltd.
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Web of science
Create date
25/01/2008 13:13
Last modification date
20/08/2019 12:58
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