Twenty-year trends in the prevalence of modifiable cardiovascular risk factors in young acute coronary syndrome patients hospitalized in Switzerland.
Details
Serval ID
serval:BIB_20FB38159CB2
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Twenty-year trends in the prevalence of modifiable cardiovascular risk factors in young acute coronary syndrome patients hospitalized in Switzerland.
Journal
European journal of preventive cardiology
Working group(s)
AMIS Plus Investigators
Contributor(s)
Lessing P., Hess F., Simon R., Hangartner P.J., Hufschmid U., Jeger R., Altwegg L., Schönfelder A., Windecker S., Pilgrim T., Loretan P., Roethlisberger C., Evéquoz D., Mang G., Ryser D., Niedermaier G., Kistler W., Droll A., Hongler T., Stäuble S., Freiwald G., Schmid H.P., Stauffer J.C., Cook S., Bietenhard K., Roffi M., Oertli B., Schönenberger R., Schmidli M., Federspital B., Weiss E.M., Weber K., Zender H., Steffen C., Poepping I., Hugi A., Frei J., Koltai E., Muller O., Pedrazzini G., Erne P., Cuculi F., Heimes T., Pagnamenta A., Urban P., Stettler C., Repond F., Widmer F., Heimgartner C., Polikar R., Bassetti S., Ernst S., Iselin H.U., Giger M., Egger P., Kaeslin T., Frey R., Fischer A., Herren T., Flury G., Neumeier C., Girod G., Vogel R., Niggli B., Rickli H., Nossen J., Stoller U., Bächli E., Eriksson U., Fischer T., Peter M., Gasser S., Fatio R., Wyss C., Bertel O., Maggiorini M., Stähli B., Eberli F., Christen S.
ISSN
2047-4881 (Electronic)
ISSN-L
2047-4873
Publication state
Published
Issued date
10/10/2023
Peer-reviewed
Oui
Volume
30
Number
14
Pages
1504-1512
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Publication Status: ppublish
Abstract
Modifiable cardiovascular risk factors (RFs) play a key role in the development of coronary artery disease. We evaluated 20-year trends in RF prevalence among young adults hospitalized with acute coronary syndromes (ACS) in Switzerland.
Data were analysed from the Acute Myocardial Infarction in Switzerland (AMIS) Plus registry from 2000 to 2019. Young patients were defined as those aged <50 years. Among 58 028 ACS admissions, 7073 (14.1%) were young (median 45.6 years, IQR 42.0-48.0), of which 91.6% had at least one modifiable RF and 59.0% had at least two RFs. Smoking was the most prevalent RF (71.4%), followed by dyslipidaemia (57.3%), hypertension (35.9%), obesity (21.7%), and diabetes (10.1%). Compared with older patients, young patients were more likely to be obese (21.7% vs. 17.4%, P < 0.001) and active smokers (71.4% vs. 33.9%, P < 0.001). Among young patients, between 2000 and 2019, there was a significant increase in the prevalence of hypertension from 29.0% to 51.3% and obesity from 21.2% to 27.1% (both Ptrend < 0.001) but a significant decrease in active smoking from 72.5% to 62.5% (Ptrend = 0.02). There were no significant changes in the prevalence of diabetes (Ptrend = 0.32) or dyslipidaemia (Ptrend = 0.067).
Young ACS patients in Switzerland exhibit a high prevalence of RFs and are more likely than older patients to be obese and smokers. Between 2000 and 2019, RF prevalence either increased or remained stable, except for smoking which decreased but still affected approximately two-thirds of young patients in 2019. Public health initiatives targeting RFs in young adults in Switzerland are warranted.
Data were analysed from the Acute Myocardial Infarction in Switzerland (AMIS) Plus registry from 2000 to 2019. Young patients were defined as those aged <50 years. Among 58 028 ACS admissions, 7073 (14.1%) were young (median 45.6 years, IQR 42.0-48.0), of which 91.6% had at least one modifiable RF and 59.0% had at least two RFs. Smoking was the most prevalent RF (71.4%), followed by dyslipidaemia (57.3%), hypertension (35.9%), obesity (21.7%), and diabetes (10.1%). Compared with older patients, young patients were more likely to be obese (21.7% vs. 17.4%, P < 0.001) and active smokers (71.4% vs. 33.9%, P < 0.001). Among young patients, between 2000 and 2019, there was a significant increase in the prevalence of hypertension from 29.0% to 51.3% and obesity from 21.2% to 27.1% (both Ptrend < 0.001) but a significant decrease in active smoking from 72.5% to 62.5% (Ptrend = 0.02). There were no significant changes in the prevalence of diabetes (Ptrend = 0.32) or dyslipidaemia (Ptrend = 0.067).
Young ACS patients in Switzerland exhibit a high prevalence of RFs and are more likely than older patients to be obese and smokers. Between 2000 and 2019, RF prevalence either increased or remained stable, except for smoking which decreased but still affected approximately two-thirds of young patients in 2019. Public health initiatives targeting RFs in young adults in Switzerland are warranted.
Keywords
Young Adult, Humans, Acute Coronary Syndrome/diagnosis, Acute Coronary Syndrome/epidemiology, Risk Factors, Prevalence, Switzerland/epidemiology, Cardiovascular Diseases, Diabetes Mellitus/diagnosis, Diabetes Mellitus/epidemiology, Obesity/diagnosis, Obesity/epidemiology, Hypertension/diagnosis, Hypertension/epidemiology, Dyslipidemias/diagnosis, Dyslipidemias/epidemiology, Heart Disease Risk Factors, Acute coronary syndromes, Cardiovascular disease prevention, Risk factors
Pubmed
Web of science
Open Access
Yes
Create date
24/03/2023 10:58
Last modification date
26/03/2024 8:10
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