Perioperative use of anti-platelet drugs

Details

Serval ID
serval:BIB_20C9E2DCF538
Type
Article: article from journal or magazin.
Publication sub-type
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Collection
Publications
Institution
Title
Perioperative use of anti-platelet drugs
Journal
Best Practice and Research. Clinical Anaesthesiology
Author(s)
Chassot  P. G., Delabays  A., Spahn  D. R.
ISSN
1753-3740 (Print)
Publication state
Published
Issued date
06/2007
Volume
21
Number
2
Pages
241-56
Notes
Journal Article
Review --- Old month value: Jun
Abstract
Performing a surgical procedure on a patient undergoing anti-platelet therapy raises a dilemma: is it safer to withdraw the drugs and reduce the haemorrhagic risk, or to maintain them and reduce the risk of myocardial ischaemic events? Based on recent clinical data, this review concludes that the risk of coronary thrombosis on anti-platelet drugs withdrawal is much higher than the risk of surgical bleeding when maintaining them. In secondary prevention, aspirin is a lifelong therapy and should never be stopped. Clopidogrel is mandatory as long as the coronary stents are not fully endothelialized, which takes 6-24 weeks depending on the technique used, but might be required for a longer period.
Keywords
Aspirin/therapeutic use Coronary Thrombosis/*prevention & control Hemorrhage/*chemically induced Humans Perioperative Care Platelet Aggregation Inhibitors/adverse effects/*therapeutic use Stents Surgical Procedures, Elective Ticlopidine/analogs & derivatives/therapeutic use Time Factors Treatment Outcome
Pubmed
Create date
28/01/2008 9:48
Last modification date
20/08/2019 12:57
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