Hypophosphatémie et renutrition: un effet secondaire grave méconnu [Hypophosphatemia and refeeding syndrome: a severe and underdiagnosed adverse effect].

Details

Serval ID
serval:BIB_2043359B8747
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Hypophosphatémie et renutrition: un effet secondaire grave méconnu [Hypophosphatemia and refeeding syndrome: a severe and underdiagnosed adverse effect].
Journal
Praxis
Author(s)
Monti M., Lamy O.
ISSN
1661-8157 (Print)
ISSN-L
1661-8157
Publication state
Published
Issued date
10/2003
Volume
92
Number
41
Pages
1744-1747
Language
french
Notes
Publication types: Case Reports ; Comparative Study ; English Abstract ; Journal Article
Publication Status: ppublish
Abstract
A 68-year-old woman was hospitalised because of generalised weakness and development of confusional state, related to severe hyponatremia, probably due to an eating disorder with malnutrition. During the first days of hospitalisation the patient eats surprising large amounts of food. The worsening of the confusional state in spite of normalisation of natremia, and the progressive development of anemia and thrombocytopenia, leads to the discovery of a new onset severe hypophosphatemia. The rapid fall in plasma levels of phosphorus, magnesium and potassium are the main futures of the refeeding syndrome. Its clinical manifestations are neurological, muscular, haematological and renal. The development of this syndrome is associated with a high mortality. The refeeding syndrome is seen when carbohydrates are introduced after a period of malnutrition. Identification of patients at risk for the refeeding syndrome (anorexia nervosa, chronic alcoholism, chronic malnutrition, elderly patients, oncology patients), the introduction of cautious progressive nutrition and the careful monitoring of vital signs, electrolytes levels and fluid balance, allows to prevent morbidity and mortality of this syndrome.
Keywords
Age Factors, Aged, Cachexia/diagnosis, Cachexia/therapy, Diagnosis, Differential, Eating, Feeding Methods, Female, Hospitalization, Humans, Hyponatremia/etiology, Hypophosphatemia/diagnosis, Hypophosphatemia/etiology, Malnutrition/complications, Malnutrition/diagnosis, Monitoring, Physiologic, Nutrition Therapy/adverse effects, Nutritional Support, Risk Factors, Syndrome
Pubmed
Create date
25/01/2008 13:55
Last modification date
20/08/2019 12:56
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