Pituitary lesions in multiple endocrine neoplasia syndrome (MENS) type 1.

Details

Serval ID
serval:BIB_1F5CCF36ABE4
Type
Article: article from journal or magazin.
Collection
Publications
Title
Pituitary lesions in multiple endocrine neoplasia syndrome (MENS) type 1.
Journal
Pathology, Research and Practice
Author(s)
Capella C., Riva C., Leutner M., La Rosa S.
ISSN
0344-0338 (Print)
ISSN-L
0344-0338
Publication state
Published
Issued date
1995
Peer-reviewed
Oui
Volume
191
Number
4
Pages
345-347
Language
english
Notes
Publication types: Journal Article ; ReviewPublication Status: ppublish
Abstract
This review summarizes knowledge on pathology of proliferative lesions of the pituitary gland in multiple endocrine neoplasia syndrome type 1 (MENS 1). When compared with sporadic tumors occurring in general population, pituitary adenomas associated with MENS 1 show the following distinguishing features: (1) they are more often endocrinologically functional, (2) they are more often GH or PRL-producing and (3) they are more frequently plurihormonal. The study of autoptic cases discloses that pituitary PRL or mixed GH-PRL cell adenomas in MENS are multiple and are associated with PRL or GH cell hyperplasia of the peritumoral parenchyma.
Keywords
Adenoma/pathology, Humans, Multiple Endocrine Neoplasia Type 1/pathology, Pituitary Neoplasms/pathology
Pubmed
Web of science
Create date
07/09/2016 8:46
Last modification date
20/08/2019 12:55
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