Night blindness, yellow vision, and yellow skin: symptoms and signs of malabsorption.

Détails

ID Serval
serval:BIB_1EE7C053280C
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Titre
Night blindness, yellow vision, and yellow skin: symptoms and signs of malabsorption.
Périodique
Klinische Monatsblätter Für Augenheilkunde
Auteur(s)
Pitchon E., Sahli O., Borruat F.X.
ISSN
0023-2165 (Print)
ISSN-L
0023-2165
Statut éditorial
Publié
Date de publication
05/2006
Peer-reviewed
Oui
Volume
223
Numéro
5
Pages
443-446
Langue
anglais
Notes
Publication types: Case Reports ; Journal Article
Publication Status: ppublish
Résumé
BACKGROUND: Rapidly progressing bilateral night blindness in an elderly patient suggests primarily a diagnosis of paraneoplastic retinopathy. Occasionally diffuse rod dysfunction can result from vitamin A deficiency.
HISTORY AND SIGNS: A 70-year-old man complained of progressive night blindness and xanthopsia for the past 6 months. Visual acuity was 0.8 in both eyes with severe dyschromatopsia. Slit-lamp and fundus examination were normal. Visual field disclosed bilateral depression. Scotopic full-field ERG was severely reduced. The patient's medical history revealed an acute pancreatitis one year ago, followed by chronic jaundice and an increased blood bilirubin. Serum vitamin A level was decreased to 0.1 micromol/L (normal range 1.5 to 4.0).
THERAPY AND OUTCOME: Intramuscular injections of vitamin A were provided. Subjective visual improvement was reported already one day after initiation of therapy. Scotopic full-field ERG was markedly improved 3 days after the injection and was only slightly subnormal 3 months later.
CONCLUSIONS: In developed countries, vitamin A deficiency usually results from malabsorption syndromes and manifests initially by rod more than cone dysfunction. This diagnosis should be entertained early as vitamin A supplementation induces a rapid restoration of vision.
Mots-clé
Aged, Color Vision Defects/prevention & control, Humans, Malabsorption Syndromes/diagnosis, Malabsorption Syndromes/drug therapy, Male, Night Blindness/prevention & control, Pigmentation Disorders/prevention & control, Skin Pigmentation, Vitamin A/administration & dosage, Vitamin A Deficiency/drug therapy, Xerophthalmia/prevention & control
Pubmed
Web of science
Création de la notice
28/01/2008 12:37
Dernière modification de la notice
20/08/2019 12:54
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