Article: article from journal or magazin.
Acute antihypertensive effect of angiotensin converting enzyme inhibition and calcium entry blockade.
Journal of cardiovascular pharmacology
10 Suppl 10
Publication types: Clinical Trial ; Comparative Study ; Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't - Publication Status: ppublish
The acute blood pressure response to an angiotensin converting enzyme inhibitor (enalaprilat) was compared in patients with uncomplicated essential hypertension with that obtained under similar conditions with a calcium entry blocker (nifedipine). The patients were studied after a 3 week washout period. At a 48 h interval, each patient received in randomized order either enalaprilat (5 mg i.v.) or nifedipine (10 mg p.o.). Enalaprilat and nifedipine were equally effective in acutely lowering blood pressure. However, good responders to one agent were not necessarily good responders to the other.
Adult, Angiotensin II, Blood Pressure, Enalapril, Female, Heart Rate, Humans, Hypertension, Male, Middle Aged, Nifedipine, Peptidyl-Dipeptidase A
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