Homolonto: generating homology relationships by pairwise alignment of ontologies and application to vertebrate anatomy.

Détails

Ressource 1Télécharger: BIB_1DA8753017CD.P001.pdf (144.28 [Ko])
Etat: Public
Version: de l'auteur
ID Serval
serval:BIB_1DA8753017CD
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Homolonto: generating homology relationships by pairwise alignment of ontologies and application to vertebrate anatomy.
Périodique
Bioinformatics
Auteur(s)
Parmentier G., Bastian F.B., Robinson-Rechavi M.
ISSN
1367-4811[electronic], 1367-4803[linking]
Statut éditorial
Publié
Date de publication
2010
Peer-reviewed
Oui
Volume
26
Numéro
14
Pages
1766-1771
Langue
anglais
Résumé
MOTIVATION: The anatomy of model species is described in ontologies, which are used to standardize the annotations of experimental data, such as gene expression patterns. To compare such data between species, we need to establish relations between ontologies describing different species. RESULTS: We present a new algorithm, and its implementation in the software Homolonto, to create new relationships between anatomical ontologies, based on the homology concept. Homolonto uses a supervised ontology alignment approach. Several alignments can be merged, forming homology groups. We also present an algorithm to generate relationships between these homology groups. This has been used to build a multi-species ontology, for the database of gene expression evolution Bgee. AVAILABILITY: download section of the Bgee website http://bgee.unil.ch/
Pubmed
Web of science
Open Access
Oui
Création de la notice
26/05/2010 12:52
Dernière modification de la notice
20/08/2019 12:53
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