Article: article from journal or magazin.
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Does vitamin D deficiency contribute to further impinge the state of vulnerability to infections of aging and aged adults?
European Geriatric Medicine
Interaction with the immune system is one of the most recently established non-classic effects of vitamin D (VitD) and recent reports have supported its role in promoting normal function of the innate and adaptive immune systems. Sub-optimal VitD status is a common peculiarity throughout the world and most particularly in the older population; a population presenting an increased susceptibility to infectious diseases and vaccine failure due to the age-related changes of the immune system commonly termed immunosenescence. This review will examine the current understanding of how VitD status may further impinge the immune senescence process. Furthermore, we discuss the role played by VitD in host immune response to common pathogens and to vaccinations.
Web of science
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