Article: article from journal or magazin.
Review (review): journal as complete as possible of one specific subject, written based on exhaustive analyses from published work.
Le rein de l'enfant face à la chimiothérapie [The kidney in children under chemotherapy].
Revue Médicale de la Suisse Romande
Publication types: English Abstract ; Journal Article ; ReviewPublication Status: ppublish
Nowadays more and more children survive after an intensive anti-tumoral therapy. The price to pay consists of numerous and relatively frequent long-term sequelae (secondary tumors, neuropsychological deficits, endocrine or cardiac damage). After chemotherapy, we sometimes observe renal side-effects, either tubular (metabolic acidosis, hypokalemia, hypomagnesemia, proteinuria, Fanconi syndrome, rickets) or glomerular (acute or chronic decreased GFR). These renal toxic side-effects are encountered especially after cisplatinum and ifosfamide, less frequently after carboplatin and cyclophosphamide. The pediatrician has to be aware of these toxic nephrologic side-effects, to look out for them and monitor carefully the renal function of all paediatric patients receiving these potentially nephrotoxic chemotherapies.
Antineoplastic Agents/adverse effects, Antineoplastic Agents/toxicity, Antineoplastic Agents, Alkylating/adverse effects, Carboplatin/adverse effects, Child, Cisplatin/adverse effects, Glomerular Filtration Rate/drug effects, Humans, Ifosfamide/adverse effects, Kidney/drug effects, Kidney Diseases/chemically induced, Kidney Diseases/diagnosis, Kidney Function Tests, Methotrexate/adverse effects, Mitomycin/adverse effects, Semustine/adverse effects
Last modification date