arrayMap 2014: an updated cancer genome resource.

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Version: Final published version
Serval ID
serval:BIB_1B719B230317
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
arrayMap 2014: an updated cancer genome resource.
Journal
Nucleic Acids Research
Author(s)
Cai H., Gupta S., Rath P., Ai N., Baudis M.
ISSN
1362-4962 (Electronic)
ISSN-L
0305-1048
Publication state
Published
Issued date
2015
Volume
43
Number
Database issue
Pages
D825-D830
Language
english
Abstract
Somatic copy number aberrations (CNA) represent a mutation type encountered in the majority of cancer genomes. Here, we present the 2014 edition of arrayMap (http://www.arraymap.org), a publicly accessible collection of pre-processed oncogenomic array data sets and CNA profiles, representing a vast range of human malignancies. Since the initial release, we have enhanced this resource both in content and especially with regard to data mining support. The 2014 release of arrayMap contains more than 64,000 genomic array data sets, representing about 250 tumor diagnoses. Data sets included in arrayMap have been assembled from public repositories as well as additional resources, and integrated by applying custom processing pipelines. Online tools have been upgraded for a more flexible array data visualization, including options for processing user provided, non-public data sets. Data integration has been improved by mapping to multiple editions of the human reference genome, with the majority of the data now being available for the UCSC hg18 as well as GRCh37 versions. The large amount of tumor CNA data in arrayMap can be freely downloaded by users to promote data mining projects, and to explore special events such as chromothripsis-like genome patterns.
Pubmed
Web of science
Open Access
Yes
Create date
14/04/2015 8:56
Last modification date
20/08/2019 12:52
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