FDG-PET hyperactivity pattern in anti-NMDAr encephalitis.

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State: Public
Version: Author's accepted manuscript
Serval ID
serval:BIB_1B03E19F69B4
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
FDG-PET hyperactivity pattern in anti-NMDAr encephalitis.
Journal
Journal of neuroimmunology
Author(s)
Novy J., Allenbach G., Bien C.G., Guedj E., Prior J.O., Rossetti A.O.
ISSN
1872-8421 (Electronic)
ISSN-L
0165-5728
Publication state
Published
Issued date
15/08/2016
Peer-reviewed
Oui
Volume
297
Pages
156-158
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
FDG-PET can show anteroposterior glucose metabolism gradient in anti-NMDAr encephalitis, but there are also suggestions that basal ganglia are involved. We examined FDG-PET scans in 5 consecutive episodes of serologically proven anti-NMDAr encephalitis, compared with healthy controls. We confirmed the anteroposterior metabolic gradient and found a significant FDG uptake increase in the caudate nuclei in episodes of varying intensity and delay from the onset of the symptoms. FDG-PET can be useful in the work-up of suspected anti-NMDAr encephalitis disclosing a characteristic cortical and sub-cortical metabolism pattern.

Keywords
Adult, Anti-N-Methyl-D-Aspartate Receptor Encephalitis/diagnostic imaging, Anti-N-Methyl-D-Aspartate Receptor Encephalitis/metabolism, Female, Fluorodeoxyglucose F18/metabolism, Humans, Positron-Emission Tomography, Retrospective Studies, Young Adult, Inflammation, NMDA, Psychiatry
Pubmed
Web of science
Open Access
Yes
Create date
12/07/2016 12:51
Last modification date
20/08/2019 12:51
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