The Leu33/Pro polymorphism (PlA1/PlA2) of the glycoprotein IIIa (GPIIIa) receptor is not related to myocardial infarction in the ECTIM Study. Etude Cas-Temoins de l'Infarctus du Myocarde

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Serval ID
serval:BIB_1AD1B9072D18
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Production externe
Title
The Leu33/Pro polymorphism (PlA1/PlA2) of the glycoprotein IIIa (GPIIIa) receptor is not related to myocardial infarction in the ECTIM Study. Etude Cas-Temoins de l'Infarctus du Myocarde
Journal
Thrombosis and Haemostasis
Author(s)
Herrmann S.M., Poirier O., Marques-Vidal P., Evans A., Arveiler D., Luc G., Emmerich J., Cambien F.
ISSN
0340-6245 (Print)
ISSN-L
0340-6245
Publication state
Published
Issued date
1997
Volume
77
Number
6
Pages
1179-1181
Language
english
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Abstract
The GPIIb/IIIa receptor complex may contribute to acute coronary syndromes by mediating platelet aggregation. The Leu33/Pro polymorphism (PlA1/PlA2) of the GPIIIa has recently been shown to be associated with CHD in a small case-control study. We have investigated this polymorphism in a large multicenter study of patients with myocardial infarction and controls and found no difference in the distribution of allele and genotype frequencies between cases and controls.
Keywords
Leucine/genetics, Myocardial Infarction/blood, Myocardial Infarction/genetics, Platelet Glycoprotein GPIIb-IIIa Complex/genetics
Pubmed
9241754
Web of science
A1997XJ08000026
Create date
01/12/2016 16:02
Last modification date
20/08/2019 13:51
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