Photodynamic therapy for chronic central serous chorioretinopathy.
Details
Serval ID
serval:BIB_1ABDA47363D9
Type
Article: article from journal or magazin.
Publication sub-type
Case report (case report): feedback on an observation with a short commentary.
Collection
Publications
Institution
Title
Photodynamic therapy for chronic central serous chorioretinopathy.
Journal
Retina
ISSN
0275-004X (Print)
ISSN-L
0275-004X
Publication state
Published
Issued date
12/2003
Peer-reviewed
Oui
Volume
23
Number
6
Pages
752-763
Language
english
Notes
Publication types: Case Reports ; Journal Article
Publication Status: ppublish
Publication Status: ppublish
Abstract
To determine whether photodynamic therapy (PDT) is effective for treatment of chronic central serous chorioretinopathy (CSC).
Sixteen eyes with chronic CSC and macular detachment documented by optical coherence tomography (OCT) received PDT guided by indocyanine green (ICG) angiography according to the parameters outlined in the TAP Study. One or more laser spots were applied to the areas of choroidal vascular hyperpermeability that corresponded to retinal pigment epithelium decompensation. Patients were observed for 6 to 12 months. Two PDT sessions 1 month apart were performed on 2 eyes. Examinations included visual acuity measurement, fundus biomicroscopy, fluorescein and ICG angiography, and OCT.
Macular exudation resolved completely in 13 eyes (81%) and partially regressed in 3. Choriocapillaris hypoperfusion was shown by ICG angiography for several months at the site of PDT application. Visual acuity improved 1 to 4 lines in 11 eyes and was unchanged in 5 eyes.
ICG-guided PDT performed according to the parameters outlined by the TAP Study seems effective for treating chronic CSC. Further studies are needed to verify treatment safety and the time and rate of recurrences.
Sixteen eyes with chronic CSC and macular detachment documented by optical coherence tomography (OCT) received PDT guided by indocyanine green (ICG) angiography according to the parameters outlined in the TAP Study. One or more laser spots were applied to the areas of choroidal vascular hyperpermeability that corresponded to retinal pigment epithelium decompensation. Patients were observed for 6 to 12 months. Two PDT sessions 1 month apart were performed on 2 eyes. Examinations included visual acuity measurement, fundus biomicroscopy, fluorescein and ICG angiography, and OCT.
Macular exudation resolved completely in 13 eyes (81%) and partially regressed in 3. Choriocapillaris hypoperfusion was shown by ICG angiography for several months at the site of PDT application. Visual acuity improved 1 to 4 lines in 11 eyes and was unchanged in 5 eyes.
ICG-guided PDT performed according to the parameters outlined by the TAP Study seems effective for treating chronic CSC. Further studies are needed to verify treatment safety and the time and rate of recurrences.
Keywords
Aged, Choroid Diseases/diagnosis, Choroid Diseases/drug therapy, Chronic Disease, Female, Fluorescein Angiography, Follow-Up Studies, Humans, Indocyanine Green, Male, Middle Aged, Photochemotherapy, Photosensitizing Agents/therapeutic use, Porphyrins/therapeutic use, Retinal Detachment/diagnosis, Retinal Detachment/drug therapy, Retinal Diseases/diagnosis, Retinal Diseases/drug therapy, Tomography, Optical Coherence, Treatment Outcome, Verteporfin, Visual Acuity
Pubmed
Web of science
Create date
11/03/2021 13:13
Last modification date
26/03/2021 6:35
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