Health related quality of life and manual ability 5 years after neonatal ischemic stroke.
Details
Serval ID
serval:BIB_1A0397BBE324
Type
Article: article from journal or magazin.
Collection
Publications
Institution
Title
Health related quality of life and manual ability 5 years after neonatal ischemic stroke.
Journal
European journal of paediatric neurology
Working group(s)
Swiss Neuropediatric Stroke Registry Group
Contributor(s)
Bigi S., Mori A.C., Datta A., Fluss J., Hackenberg A., Keller E., Maier O., Mercati D., Marcoz J.P., Poloni C., Ramelli G.P., Schmid R., Schmitt-Mechelke T.
ISSN
1532-2130 (Electronic)
ISSN-L
1090-3798
Publication state
Published
Issued date
09/2019
Peer-reviewed
Oui
Volume
23
Number
5
Pages
716-722
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Abstract
To investigate health-related quality of life (HRQOL) and manual ability five years after neonatal arterial ischemic stroke (NAIS).
Data was prospectively obtained by the Swiss Neuropaediatric Stroke Registry between 2000 and 2010. Two years after NAIS, cognitive and motor outcomes was assessed using the Bayley Scales of Infant Development (BSID-II). After 5 years, HRQOL was assessed with the KIDSCREEN-27 and manual ability with the ABILHAND-Kids. Manual ability and HRQOL were compared between children with and without cerebral palsy (CP) and HRQOL was correlated with manual ability.
Seventy-four patients were examined at the age of 2 years, at the age of 5 years 61 patients underwent a follow-up examination. Two years after NAIS, 29 children (39.1%) were diagnosed with CP. HRQOL 5 years after NAIS was comparable to normative values. Children with CP had a significantly lower HRQOL-index (p = 0.013) and lower scores in the subscale psychological well-being (p = 0.012) and social support & peers (p = 0.048). The ABILHAND-Kids measure was significantly lower in children with CP compared to children without CP (p < 0.001). Manual ability correlated significantly with HRQOL.
Five years after NAIS, HRQOL is comparable to that of typically developing peers, but reduced in children with CP. Poorer manual ability is associated with lower HRQOL. Interventions improving hand function might influence HRQOL and should be considered early on.
Data was prospectively obtained by the Swiss Neuropaediatric Stroke Registry between 2000 and 2010. Two years after NAIS, cognitive and motor outcomes was assessed using the Bayley Scales of Infant Development (BSID-II). After 5 years, HRQOL was assessed with the KIDSCREEN-27 and manual ability with the ABILHAND-Kids. Manual ability and HRQOL were compared between children with and without cerebral palsy (CP) and HRQOL was correlated with manual ability.
Seventy-four patients were examined at the age of 2 years, at the age of 5 years 61 patients underwent a follow-up examination. Two years after NAIS, 29 children (39.1%) were diagnosed with CP. HRQOL 5 years after NAIS was comparable to normative values. Children with CP had a significantly lower HRQOL-index (p = 0.013) and lower scores in the subscale psychological well-being (p = 0.012) and social support & peers (p = 0.048). The ABILHAND-Kids measure was significantly lower in children with CP compared to children without CP (p < 0.001). Manual ability correlated significantly with HRQOL.
Five years after NAIS, HRQOL is comparable to that of typically developing peers, but reduced in children with CP. Poorer manual ability is associated with lower HRQOL. Interventions improving hand function might influence HRQOL and should be considered early on.
Keywords
Brain Ischemia/complications, Cerebral Palsy/etiology, Child, Child, Preschool, Female, Humans, Infant, Infant, Newborn, Male, Quality of Life, Recovery of Function, Stroke/complications, Cerebral palsy, Hemiparesis, Manual ability, Neonatal arterial ischemic stroke, Quality of life
Pubmed
Web of science
Create date
07/01/2020 12:58
Last modification date
23/04/2024 6:59
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