CD14 and LBP in endotoxemia and infections caused by Gram-negative bacteria.

Détails

ID Serval
serval:BIB_19613
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
CD14 and LBP in endotoxemia and infections caused by Gram-negative bacteria.
Périodique
Journal of Endotoxin Research
Auteur(s)
Heumann D.
ISSN
0968-0519 (Print)
ISSN-L
0968-0519
Statut éditorial
Publié
Date de publication
2001
Volume
7
Numéro
6
Pages
439-441
Langue
anglais
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Résumé
It is now well recognized that plasma LPS-binding protein (LBP) and membrane CD14 present at the surface of cells of the myelo/monocytic lineage are central molecules of the innate immune system, in response to LPS or to bacterial products. This paper reviews the role of LBP and CD14 in models of endotoxemia and infection.
Mots-clé
Acute-Phase Proteins, Animals, Antibodies, Monoclonal/therapeutic use, Antigens, CD14/genetics, Antigens, CD14/physiology, Carrier Proteins/genetics, Carrier Proteins/physiology, Disease Models, Animal, Endotoxemia/immunology, Endotoxemia/prevention & control, Gram-Negative Bacterial Infections/immunology, Membrane Glycoproteins, Mice, Mice, Knockout
Pubmed
Web of science
Création de la notice
19/11/2007 13:14
Dernière modification de la notice
03/03/2018 14:26
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