Composite freestyle stentless xenograft with Dacron graft extension for ascending aortic replacement.

Details

Serval ID
serval:BIB_1926BF3B4E8A
Type
Article: article from journal or magazin.
Collection
Publications
Title
Composite freestyle stentless xenograft with Dacron graft extension for ascending aortic replacement.
Journal
The Annals of thoracic surgery
Author(s)
Zannis K., Deux J.F., Tzvetkov B., Nakashima K., Loisance D., Rahmouni A., Kirsch M.E.
ISSN
1552-6259 (Electronic)
ISSN-L
0003-4975
Publication state
Published
Issued date
06/2009
Peer-reviewed
Oui
Volume
87
Number
6
Pages
1789-1794
Language
english
Notes
Publication types: Journal Article
Publication Status: ppublish
Abstract
The present study was undertaken to evaluate clinical, hemodynamic, and morphologic results of composite stentless xenograft with polyethylene terephthalate fiber (Dacron; DuPont, Wilmington, DE) graft extension for combined replacement of the aortic valve, root, and ascending aorta.
Between 1997 and 2008, 55 consecutive patients (33 men, 71 +/- 11 years) underwent ascending aortic replacement using Medtronic Freestyle with Dacron graft extension (DuPont). Indications included aneurysm (n = 31, 56%), dissection (n = 16, 29%), and endocarditis (n = 8, 15%). Associated procedures were performed in 25 patients (46%). Preoperative logistic EuroSCORE averaged 34% +/- 28%. Mean cardiopulmonary bypass and aortic cross-clamp times were 244 +/- 134 minutes and 162 +/- 69 minutes, respectively.
Clinical follow-up was 100% complete and averaged 2 +/- 3 years. Early mortality was 0% (n = 0) in patients with a preoperative EuroSCORE of less than 20 (n = 26, mean expected mortality, 13% +/- 5%) and 31% (n = 9) in those with preoperative logistic EuroSCORE of at least 20 (n = 29, mean expected mortality, 52% +/- 28%). One- and 3-year survival rates were 83% +/- 5% and 78% +/- 7%, respectively. No major thromboembolic or spontaneous bleeding events were recorded. One patient (2%) required late reoperation for prosthetic valve endocarditis. Echocardiographic follow-up showed no valve dysfunction and low mean transvalvular gradients (7 +/- 5 mm Hg). A 64-channel computed tomographic scan was performed in 33 patients at 32.4 +/- 34 months and revealed two small pseudoaneurysms in a single patient.
Composite Freestyle with Dacron graft extension appears to be a safe option for bioprosthetic replacement of the aortic root and tubular ascending aorta. However, long-term results using this composite graft will have to be determined.
Keywords
Aged, Aorta/surgery, Blood Vessel Prosthesis/adverse effects, Cohort Studies, Female, Humans, Male, Polyethylene Terephthalates/adverse effects, Postoperative Complications/epidemiology, Retrospective Studies
Pubmed
Web of science
Create date
29/03/2019 7:11
Last modification date
20/08/2019 12:49
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